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Four horses test positive for equine herpes virus

October 27, 2006

The four positive tests came out of a group of 11 horses that were tested. William Keegan, the veterinarian caring for the horses, said the results of the other tests were expected back by Thursday morning.

The barn housing all 11 horses has been under quarantine since Sunday, when five horses were found to have fevers. None of the horses stabled at Monmouth Park has been allowed to race out of state, and all horses that have raced at the Meadowlands Racetrack have been required to return to Monmouth for a period of 12 days, the incubation period for the virus.

That requirement extends to out-of-state horses that race at the Meadowlands. Wednesday and Thursday night’s programs at the Meadowlands were scheduled to feature only horses shipped from Monmouth Park.

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Equine herpes virus produces flu-like symptoms such as upper respiratory infections and a high fever. In severe cases, it can attack a horse’s nervous system and affect coordination and balance and can lead to the horse being euthanized. It is transmitted through contact between horses, similar to a human cold, but does not affect humans.

None of the Monmouth horses exhibited any neurological symptoms, according to Keegan, although results of neurological tests had not yet been received by Wednesday evening.

“I feel like we caught this early enough to contain it and nip it in time,” Keegan said.

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And the Caissons go Rolling Along

October 24, 2006

We met one night at Premiere. Scratch that. We fought one night at Premiere.

As per the norm these days (and abetted by an increasing propensity for “rum and diet —two limes”), I deemed it completely appropriate to immediately berate his entire existence. Granted, it may not be smart to tell a perfect stranger that he, in effect, is the root of society’s evil or to casually nominate him Bush’s idiotic, zombie minion. I just couldn’t help myself. He was a Navy Guy.

Navy Guy, yes. But also cute as hell and disarmingly charming. In what proved to be a rare move, I ditched my friends— flirting and fighting with my newfound blue-eyed nemesis the rest of the night.

Both the hours and the drinks bolted by as we perched against the bar, oblivious to the pulsing scene vibrating around us. My proclivity for aggressive political argumentation was in full effect, eventually trumped only by my competing proclivity for dancing. He became my anchor, the only thing ensuring maintenance of vertical orientation as I teetered and swayed in 4-inch heels.

The more and more blurry night inevitably (and thankfully) ended when my liquored-up behind was dragged off the dance floor by my girlfriend-cum-babysitter — leaving Navy Guy in my unfortunate and Elaine Benice-esque wake. I didn’t say goodbye.

In a twist of fate, or stalkerdom, or Satan’s will, he tracked me down. I hated him and he tracked me down. He emailed me at work. I agreed to a date. We went out. A few times. I hated myself. I was starting to like him.

On one particularly wrathful afternoon we rode around in a thunderstorm, listening to music and the dull sound of late summer raindrops pounding on the plastic windows of his jeep. We rocked out at The Strokes concert, clapping and singing the show through. We kissed in elevators. We talked a good deal about the war, not much about ourselves. We kissed in the parking deck.

The odds of my attraction to his particular “type” were about the same as my odds of soliciting dates at the local herpes treatment center or picking them out of the sexual offender database on the web. Hell, he may as well have had waxed eyebrows or been wearing capri pants.

Not only was he a Third-Class-Sergeant-Sailor-Special-Agent-Bushie-Slave-Robot-Whatever, he was soon shipping out to the Middle East.

I’ve never once been conflicted about matters of the head. I’ve never once questioned my disdain for this administration’s foreign policy. I’ve never once felt the need to blindly support American endeavors for the sole declaration of patriotism. In this, I am unwavering.

Matters of the heart are a different story, and this matter of the heart made me want to scream and cry in a big, conflicted mess. It bled the line distinguishing my thoughts from my feelings a little too much; it left me raw.

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Compounded by deadline and exacerbated by immediacy, I felt the need to protect my rotten little insides.

Self-preservation is a bitch and I found myself staring her in the mean, ugly face. For a girl whose motto is an only half-cheeky “Whatever, I do what I want,” wanting something that was clearly not intelligent was not an easy thing to keep from doing.

As I felt myself slip and my thoughts wandering to things like coffins (that’s what they call the beds on the ship, I was told), I couldn’t help but wonder, what was the point? Why did I even care? The issue, the navy boy, was moot.

Had this been any normal circumstance, the future would not be a concern until, well, it became the present. But this was not normal and time was operating on a warped-speed plane beyond my control.

We shared no more than two months of combustible chemistry—sparked by playful battling over vastly cleaving values and dotted with too-hot-for-publication text-messages. (Yes, text messages.) I can’t speak for my sparring partner, but I spent a whole lot of time pondering our next bout in the ring.

I realized I was becoming vulnerable to this man: the antithesis of all I desired. I freaked out. I got all weird. In my head at least, I started to become That Girl.

Stupid Navy Guy had turned casual me into That Girl and I didn’t like it. Not at all. So I took a few deep breaths (which really didn’t help) and moped over a bottle of Riesling and the entire first season of Grey’s Anatomy (which really kinda did).

I knew I wasn’t going to wait around for him while he was at sea, but I also knew that his pouty lips on mine made the hairs on the back of my neck stand at attention and that the way he looked at me was not the way most men do.

We drove out to the beach on Tuesday and spent the night not talking about his leaving. I’m glad I didn’t meet him sooner.

Posted by toshko under Herpes News | Comments (0)

Few Patients at Risk for Carrying Genital Herpes Get Tested for the Infection: Presented at IDSA

October 18, 2006

Few individuals who are at risk of contracting herpes simplex virus-2, the cause of genital herpes, have been tested for the disease, researchers said here at the Infectious Diseases Society of America (IDSA) 44th Annual Meeting.

Zane Brown, MD, professor of maternal-fetal medicine, University of Washington, Seattle, Washington, and colleagues reviewed records of the Integrated Healthcare Information Services that includes information on 30 health plans in the United States and a population of nearly 10.9 million people.

Based on published literature and clinician opinion, the researchers selected 255 different International Classification of Diseases Ninth Revision, Clinical Modification (ICD-9-CM) codes to identify patients at risk for genital herpes.

At-risk conditions include infection with HIV or other sexually transmitted diseases, genealogical conditions and men’s health issues, pregnancy, hemorrhoids, allergies, dermatologic conditions, gastrointestinal problems and certain urinary complaints.

To examine the proportion of at risk patients in the total population, the researchers also applied the same ICD-9-CM codes to the total population.

They identified 6,924,977 individuals in that database who were at risk of contracting genital herpes.

Out of the entire population of patients, 47,992 people were actually tested for genital herpes, including 40,691 who fit into the at-risk categories for testing. This means that of all the people who should have been tested for genital herpes, 0.6% were actually tested, Dr. Brown said.

The database information does not indicate what proportion of patients were found to be positive for genital herpes, but 19% of patients who were tested were subsequently prescribed antiviral medications and 79% received no medications.

“This study highlights the need for increased use of diagnostic testing among patients at risk for acquiring genital herpes,” he said in his poster presentation on October 13th.

Dr. Brown noted that about 20% of the US population is believed to be infected with the genital herpes but 70% to 90% of the people who are infected are not aware of their status.

“Increasing testing of genital herpes could help not only with diagnosis of disease, but also with appropriate management and treatment of genital herpes and it could aid in prevention or transmission of the disease,” Dr. Brown suggested.

The study received support from GlaxoSmithKline, Research Triangle Park, North Carolina, USA, and Collegeville, Pennsylvania, USA.

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Research Holds Promise For Herpes Vaccine

October 16, 2006

A study by a Montana State University researcher suggests a new avenue for developing a vaccine against genital herpes and other diseases caused by herpes simplex viruses.

In a study published earlier this year in the Virology Journal, MSU virologist William Halford showed that mice vaccinated with a live, genetically-modified herpes simplex virus type 1 (HSV-1) showed no signs of disease 30 days after being exposed to a particularly lethal “wild-type” strain of the virus.

In contrast, a second group of mice that received a more conventional vaccine died within six days of being exposed to the same “wild-type” strain.

“We have a clear roadmap for producing an effective live vaccine against genital herpes,” said Halford, who works in MSU’s Department of Veterinary Molecular Biology. “Although my studies were performed with HSV-1, the implications for HSV-2-induced genital herpes are clear. Overall the two viruses are about 99 percent genetically identical.”

An estimated 55 million Americans carry herpes simplex virus type 2 (HSV-2), which causes genital herpes. Infection is life-long. Approximately 5 percent of those with genital herpes - 2 million to 3 million Americans - suffer outbreaks one to four times annually. A vaccine offering life-long protection does not exist.

The key to Halford’s research was understanding how the herpes simplex virus overcame the body’s natural defenses.

A cell infected with the herpes simplex virus sends a warning to neighboring cells. This warning — an interferon response — causes neighboring cells to enter “an anti-viral state” akin to putting on a suit of armor, Halford said.

However, herpes produces a protein, ICP0, that tricks every infected cell into destroying its own armor. Once the cell’s armor is gone, the virus can propagate itself and spread to other cells, which are in turn tricked into lowering their defenses.

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In his research, Halford created a vaccine where the genetic instructions that make ICP0 were disrupted. Without instructions on how to do its clever ICP0 trick, the virus can still establish an infection in animals, but the spread of the virus is stopped long before disease can occur.

“In short, we can disarm the virus such that it is absolutely unable to cause disease, but is still remarkably potent as a vaccine,” Halford said.

In a human vaccine, the genetic instructions for ICP0 would actually be removed, creating an “attenuated,” or weakened virus. The rest of the herpes simplex virus’ genetic code would remain intact. Measles, mumps, rubella, polio and yellow fever vaccines are all made from attenuated viruses.

Research in recent decades has focused on subunit vaccines, which are made from one piece of a virus (a protein subunit). Subunit vaccines are safer than attenuated virus vaccines because the subunit cannot replicate or cause disease. However, subunit vaccines have proven ineffective in protecting people against persistent infections like genital herpes and AIDS, Halford said.

“From a theoretical standpoint, subunit vaccines are poor mimics of a natural virus infection,” Halford said. “There’s not enough there for our immune systems to build a protective response against the actual virus.”

Halford, 38, is aware that his approach is controversial.

“This is where I’m young enough that I don’t know how long it can take to swing popular opinion among scientists and clinicians,” he said. “I would hope that in five to six years the scientific community would be willing to seriously consider these proposals.”

Halford hopes to find a commercial partner or secure government funding to advance his research toward a human vaccine.

“I’d like to take this concept from the chalkboard to the clinics,” he said

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Oral Lesions Are Commonly Associated With Pediatric HIV

October 11, 2006

Across the globe, the presence of HIV is wide-spread. At the end of 2004, the United Nations HIV/AIDS program estimated that 2.5 million children under the age of 15 were affected worldwide. Additionally, approximately 500,000 children in that same age group died from disease-related cases in that year alone. In the United States, 90 percent of infected children are infected by the disease through birth.

The effects of the disease on children differ greatly from those in adults, according to a report/study that appears in the July/August 2006 issue of General Dentistry, the AGD’s clinical, peer-reviewed journal. Type, severity and progression are all factors that differ, depending on the age at which one contracts the disease.

“Children do not demonstrate HIV-specific symptoms as adults do,” says Kishore Shetty, DDS, lead author of the study. “Their bodies will most likely display an infection or weakness instead of common HIV signs.”

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The place where this most commonly occurs is in the mouth. There are many variations of the way lesions appear, but a few common types are: candidiasis, or “thrush,” a fungal yeast infection; salivary gland enlargement; herpes simplex virus; inflammation of the gingiva; and canker sores.

“Orofacial manifestations of HIV are common in pediatric HIV infection,” Shetty adds. “It is important to be aware of these signs, as they may serve as both a marker of infection and predictor of HIV progressing to AIDS.”

What to do:

Visit your general dentist. They handle the majority of dental emergencies.

If you fear that your child or teen might be at risk, have them tested as soon as possible. The sooner a child is diagnosed, the sooner treatment can begin.

Communicate with your dentist if the child has HIV. It will alert them to look closely for signs of disease, plus allow them to provide the best possible treatment.

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New Doctor Tests Imulux Herpes Treatment at Health Center in India

October 10, 2006

Dr. Jonathan Dao and his wife, Dr. Jenni Saukkonen, have announced they will be testing a new process this month for treating Herpes at the Blue Planet Nature Cure Center in Goa, India. Several doctors in the United States have already announced they will incorporate the procedure, known as the Imulux Herpes Treatment Imulux Herpes Treatment, into their practices as a standard procedure for treating herpes.

Dr. Dao and Dr. Saukkonen have operated the center for about three years. Dr. Dao said if the trials prove successful, they will incorporate the Imulux herpes treatment into their practices.

“We get a large number of patients that suffer from herpes,� said Dr. Dao. He was first informed of the treatment’s existence last month, he said.

Doctors at the center will apply the Imulux herpes treatment in conjunction with traditional herbal medicines of India drawn from the practices of Ayurveda and Yoga-based therapy.

Dr. Dao said they will use the Imulux herpes treatment at locations in Geneva and Bangkok where they serve as consultants if the trials are successful.

He said the Imulux herpes treatment uses ultraviolet light as part of its treatment, which is part of what interested him in using this treatment. Dr. Dao made references to how this ultraviolet light is also used in India to purify water.

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“You are not using any medication at all,� he said regarding the Imulux herpes treatment.

Clinicians and investigators associated with clinical trials for the Imulux herpes treatment have praised its performance. The trials included extensive interviews with patients before and after the herpes treatment, which clinicians said reflected its success.

Therefore as a result, Dr. Dao would like to use the Imulux herpes treatment in his center and test it on his patients. If successful, Dr. Dao will fully incorporate the Imulux herpes treatment into his practice.

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